betamethasone can significantly decrease level of striatal glutamate in animal model of parkinson's disease
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abstract
in the present study, the effect of steroidal anti-inflammatory drug betamethasone (0.12, 0.24 mg/kg, i.p. acutely) on striatal glutamate level in parkinsonian rats was studied using the microdialysis technique. our results showed significant differences (p<0.05) in the level of striatal glutamate between treated and non-treated damaged rats.
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Journal title:
iranian journal of pharmaceutical researchجلد ۲۰۰۸، شماره ۷، صفحات ۲۲۹-۲۳۲
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